Pusat Studi Oral Biologi Molekuler

Pusat Studi Oral Biologi Molekuler

Pusat Studi Oral Biologi Molekuler adalah unit akademik atau penelitian di institusi pendidikan tinggi yang fokus pada kajian dan penelitian tentang aspek molekuler dari biologi oral. Pusat studi ini berfokus pada pemahaman proses-proses biologis dan molekuler yang terjadi di rongga mulut dan bagaimana mereka memengaruhi kesehatan gigi dan mulut.

1. Struktur Organisasi

2. Bidang kajian

  1. Microbial Study
  2. Pharmacological Study
  3. Molecular Study
  4. Molecular Diagnostic Study

3. Alur Kerja

 

4. Kegiatan Penelitian dan Hasil Luaran Pusat Studi

a. Kegiatan Penelitian

No

Tahun Judul Penelitian

Peneliti Dosen/mahasiswa

1 2021 Karakteristik Sel Polip Pulpa Sebagai Sel Punca Mesenkimal (Kajian Terhadap Protein Permukaan pada Sel Polip Pulpa) drg. Ferry Sandra, Ph.D. dkk
2 2020 Karakteristik Sel Polip Pulpa Sebagai Sel Punca Mesenkimal (Kajian Terhadap Protein Permukaan pada Sel Polip Pulpa) (laporan penelitian) drg. Ferry Sandra, Ph.D. dkk
3 2020 Histon Meningkatkan Kemampuan Inositol Heksakisfosfat dalam Menimbulkan Apoptosis Sel Kanker Mulut drg. Ferry Sandra, Ph.D. dkk
4 2020 Kemampuan Diferensiasi Dental Pulp Stem Cell menjadi Inner Ear Hair Cell drg. Ferry Sandra, Ph.D. dkk
5 2019 Histon Meningkatkan Kemampuan Inositol Heksakisfosfat dalam Menimbulkan Apoptosis Sel Kanker Mulut (laporan penelitian) drg. Ferry Sandra, Ph.D. dkk
6 2019 Karakteristik Fenotif Sel Punca Pulpa Molar 3 Fakultas Kedokteran Gigi Universitas Trisakti drg. Ferry Sandra, Ph.D. dkk
7 2019 Conditioned Media Human Umbilical Cord Blood Mesenchymal  Stem Cell Menghambat Induksi Apoptosis oleh Ultraviolet B drg. Ferry Sandra, Ph.D. dkk
 b. Hasil Luaran Pusat Studi
No Publikasi Penelitian Tahun Peneliti Jurnal
1 Crucial Triad in Pulp-Dentin Complex Regeneration: Dental Stem Cells, Scaffolds, and Signaling Molecules 2023 drg. Ferry Sandra, Ph.D. The Indonesian Biomedical Journal
2 Curcuma xanthorrhiza Rhizome Extract Induces Apoptosis in HONE-1 Nasopharyngeal Cancer Cells Through Bid The Indonesian Biomedical Journal
3 Eleutherine bulbosa bulb extract induces apoptosis and inhibits cell migration by downregulating Sonic hedgehog in human tongue cancer cells: An in vitro study Indian Journal of Biochemistry and Biophysics
4 Parkia speciosa seeds ethanol extract as co-chemotherapeutic agent for doxorubicin toward tongue cancer 2022 The Indonesian Biomedical Journal
5 Differentiation capacity of dental pulp stem cell into inner ear hair cell using an in vitro assay: a preliminary step toward treating sensorineural hearing loss
 

European Archives of Oto-Rhino-Laryngology

 

6 Potensi chamomile sebagai agen antiinflamasi oral 2023 drg. Ria Aryani H., M.Sc. Jurnal Kedokteran Gigi Terpadu
7 Smoking effect on the interleukin-1β expression and periodontal status of periodontitis patients 2022 Scientific Dental Journal
8 The collagen structure of C1q induces wound healing by engaging discoidin domain receptor 2 2021 Biomed Central
9 Inflachromene inhibits autophagy through modulation of Beclin 1 activity 2018 Journal of Cell Science
10 Color Palettes Overview After Thresholding Process with Default Methods of ImageJ or FIJI 2022 Dr. Erni Erfan, S.Pd., M.Biomed Association for Computing Machinery Digital Library
11 Choline-deficient high-fat diet-induced steatohepatitis in BALB/c mice 2021 Molecular and Cellular Biomedical Sciences
12 Enzymatic activity of bromelain isolated pineapple (Ananas comosus) hump and its antibacterial effect on Enterococcus faecalis 2018 Scientific Dental Journal
13 Effects of Clitoria ternatea linn. flower juice on the elasticity, texture and pores of the denture retainer component IOP Science Publishing
14 Efek potensiasi kombinasi sefadroksil dan ekstrak camellia sinensis terhadap pertumbuhan aggregatibacter actinomycetemcomitans Dan porphyromonas gingivalis 2023 Dr. drg. Didi Nugroho S., M.Sc. Jurnal Kedokteran Gigi Terpadu
15 Efektivitas Kombinasi Natrium Hipoklorit dengan Lansoprazole dalam Menghambat Enterococcus faecalis dan Eschericia coli 2022

 

Jurnal Kedokteran Gigi Terpadu
16 Efficacies of mineral trioxide aggregate and bioceramic root canal sealer with two types of gutta-percha toward the apical leakage Scientific Dental Journal
17 The potential of reuterin derived from Indonesian strain of Lactobacillus reuteri against endodontic pathogen biofilms in vitro and ex vivo 2023 Dr. drg. M. Ihsan Rizal, M.Kes. The Saudi Dental Journal
18 Short- term effect of probiotic Lactobacillus reuteri consumption on the salivary microbiome profile of subjects undergoing orthodontic treatment with fixed appliances 2022 Taylor and Francis
19 Caffeic acid induces intrinsic apoptotic pathway in mg-63 osteosarcoma cells through bid truncation and cytochrome c release The Indonesian Biomedical Journal
20 Smoking effect on the interleukin-1β expression and periodontal status of periodontitis patients The Open Dentistry Journal
21 The red and orange complex subgingival microbiome of cognitive impairment and cognitively normal elderly with periodontitis MDPI
22 Cd8+ expression in oral potentially malignant disorders associated with risk factors in selected population of east Indonesia 2023 drg. Firstine K.H., MClinDent, Sp.PM Jurnal UNISSULA
23 The emerging concern of oral pemphigus vulgaris arising post-COVID-19 infection: A case series Journal of Oral and Maxillofacial Pathology
24 Pleomorphic rhabdomyosarcoma of the tongue in adult mimicking oral squamous cell carcinoma 2019 Scientific Dental Journal
25 A case report of Angiosarcoma of maxillary gingiva: histopathology aspects 2018 Jurnal Kedokteran Gigi Terpadu

5. Rencana kerja 2024-2026

  • Laboratory quality control
  • Pengajuan ISO laboratorium
  • Perencanaan pengadaan animal facility
  • Melakukan pelatihan skill laboratorium
  • Mengadakan scientific meeting
  • Publikasi kerjasama antar departemen
  • Membuat alur pengadaan kebutuhan reagent
  • Penamaan “Center of (Oral) Molecular Biology Study” pada publikasi
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