Pusat Studi Oral Biologi Molekuler adalah unit akademik atau penelitian di institusi pendidikan tinggi yang fokus pada kajian dan penelitian tentang aspek molekuler dari biologi oral. Pusat studi ini berfokus pada pemahaman proses-proses biologis dan molekuler yang terjadi di rongga mulut dan bagaimana mereka memengaruhi kesehatan gigi dan mulut.
1. Struktur Organisasi
2. Bidang kajian
- Microbial Study
- Pharmacological Study
- Molecular Study
- Molecular Diagnostic Study
3. Alur Kerja
4. Kegiatan Penelitian dan Hasil Luaran Pusat Studi
a. Kegiatan Penelitian
No |
Tahun | Judul Penelitian |
Peneliti Dosen/mahasiswa |
1 | 2021 | Karakteristik Sel Polip Pulpa Sebagai Sel Punca Mesenkimal (Kajian Terhadap Protein Permukaan pada Sel Polip Pulpa) | drg. Ferry Sandra, Ph.D. dkk |
2 | 2020 | Karakteristik Sel Polip Pulpa Sebagai Sel Punca Mesenkimal (Kajian Terhadap Protein Permukaan pada Sel Polip Pulpa) (laporan penelitian) | drg. Ferry Sandra, Ph.D. dkk |
3 | 2020 | Histon Meningkatkan Kemampuan Inositol Heksakisfosfat dalam Menimbulkan Apoptosis Sel Kanker Mulut | drg. Ferry Sandra, Ph.D. dkk |
4 | 2020 | Kemampuan Diferensiasi Dental Pulp Stem Cell menjadi Inner Ear Hair Cell | drg. Ferry Sandra, Ph.D. dkk |
5 | 2019 | Histon Meningkatkan Kemampuan Inositol Heksakisfosfat dalam Menimbulkan Apoptosis Sel Kanker Mulut (laporan penelitian) | drg. Ferry Sandra, Ph.D. dkk |
6 | 2019 | Karakteristik Fenotif Sel Punca Pulpa Molar 3 Fakultas Kedokteran Gigi Universitas Trisakti | drg. Ferry Sandra, Ph.D. dkk |
7 | 2019 | Conditioned Media Human Umbilical Cord Blood Mesenchymal Stem Cell Menghambat Induksi Apoptosis oleh Ultraviolet B | drg. Ferry Sandra, Ph.D. dkk |
b. Hasil Luaran Pusat Studi
No | Publikasi Penelitian | Tahun | Peneliti | Jurnal | |
1 | Crucial Triad in Pulp-Dentin Complex Regeneration: Dental Stem Cells, Scaffolds, and Signaling Molecules | 2023 | drg. Ferry Sandra, Ph.D. | The Indonesian Biomedical Journal | |
2 | Curcuma xanthorrhiza Rhizome Extract Induces Apoptosis in HONE-1 Nasopharyngeal Cancer Cells Through Bid | The Indonesian Biomedical Journal | |||
3 | Eleutherine bulbosa bulb extract induces apoptosis and inhibits cell migration by downregulating Sonic hedgehog in human tongue cancer cells: An in vitro study | Indian Journal of Biochemistry and Biophysics | |||
4 | Parkia speciosa seeds ethanol extract as co-chemotherapeutic agent for doxorubicin toward tongue cancer | 2022 | The Indonesian Biomedical Journal | ||
5 | Differentiation capacity of dental pulp stem cell into inner ear hair cell using an in vitro assay: a preliminary step toward treating sensorineural hearing loss | ||||
European Archives of Oto-Rhino-Laryngology
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6 | Potensi chamomile sebagai agen antiinflamasi oral | 2023 | drg. Ria Aryani H., M.Sc. | Jurnal Kedokteran Gigi Terpadu | |
7 | Smoking effect on the interleukin-1β expression and periodontal status of periodontitis patients | 2022 | Scientific Dental Journal | ||
8 | The collagen structure of C1q induces wound healing by engaging discoidin domain receptor 2 | 2021 | Biomed Central | ||
9 | Inflachromene inhibits autophagy through modulation of Beclin 1 activity | 2018 | Journal of Cell Science | ||
10 | Color Palettes Overview After Thresholding Process with Default Methods of ImageJ or FIJI | 2022 | Dr. Erni Erfan, S.Pd., M.Biomed | Association for Computing Machinery Digital Library | |
11 | Choline-deficient high-fat diet-induced steatohepatitis in BALB/c mice | 2021 | Molecular and Cellular Biomedical Sciences | ||
12 | Enzymatic activity of bromelain isolated pineapple (Ananas comosus) hump and its antibacterial effect on Enterococcus faecalis | 2018 | Scientific Dental Journal | ||
13 | Effects of Clitoria ternatea linn. flower juice on the elasticity, texture and pores of the denture retainer component | IOP Science Publishing | |||
14 | Efek potensiasi kombinasi sefadroksil dan ekstrak camellia sinensis terhadap pertumbuhan aggregatibacter actinomycetemcomitans Dan porphyromonas gingivalis | 2023 | Dr. drg. Didi Nugroho S., M.Sc. | Jurnal Kedokteran Gigi Terpadu | |
15 | Efektivitas Kombinasi Natrium Hipoklorit dengan Lansoprazole dalam Menghambat Enterococcus faecalis dan Eschericia coli | 2022
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Jurnal Kedokteran Gigi Terpadu | ||
16 | Efficacies of mineral trioxide aggregate and bioceramic root canal sealer with two types of gutta-percha toward the apical leakage | Scientific Dental Journal | |||
17 | The potential of reuterin derived from Indonesian strain of Lactobacillus reuteri against endodontic pathogen biofilms in vitro and ex vivo | 2023 | Dr. drg. M. Ihsan Rizal, M.Kes. | The Saudi Dental Journal | |
18 | Short- term effect of probiotic Lactobacillus reuteri consumption on the salivary microbiome profile of subjects undergoing orthodontic treatment with fixed appliances | 2022 | Taylor and Francis | ||
19 | Caffeic acid induces intrinsic apoptotic pathway in mg-63 osteosarcoma cells through bid truncation and cytochrome c release | The Indonesian Biomedical Journal | |||
20 | Smoking effect on the interleukin-1β expression and periodontal status of periodontitis patients | The Open Dentistry Journal | |||
21 | The red and orange complex subgingival microbiome of cognitive impairment and cognitively normal elderly with periodontitis | MDPI | |||
22 | Cd8+ expression in oral potentially malignant disorders associated with risk factors in selected population of east Indonesia | 2023 | drg. Firstine K.H., MClinDent, Sp.PM | Jurnal UNISSULA | |
23 | The emerging concern of oral pemphigus vulgaris arising post-COVID-19 infection: A case series | Journal of Oral and Maxillofacial Pathology | |||
24 | Pleomorphic rhabdomyosarcoma of the tongue in adult mimicking oral squamous cell carcinoma | 2019 | Scientific Dental Journal | ||
25 | A case report of Angiosarcoma of maxillary gingiva: histopathology aspects | 2018 | Jurnal Kedokteran Gigi Terpadu |
5. Rencana kerja 2024-2026
- Laboratory quality control
- Pengajuan ISO laboratorium
- Perencanaan pengadaan animal facility
- Melakukan pelatihan skill laboratorium
- Mengadakan scientific meeting
- Publikasi kerjasama antar departemen
- Membuat alur pengadaan kebutuhan reagent
- Penamaan “Center of (Oral) Molecular Biology Study” pada publikasi